Research

In my PhD research, I am aiming to bridge in vitro and in silico techniques to classify and to understand the mechanism of action of somatic histone mutations observed in cancer patients by using molecular biology, bioinformatics and epigenetics.

Publications

J. Shu, S. Li, R. R. Ospina, E. Rizk, V. Pozharskaia, A. Croteau, Y. Sheng, A. Kuznetsova, A. Macklem, L. G. Duhaime, D. Espiritu, N. Dickie, M. Li, J. Côté, C. Musselman, A. R. Panchenko, M. J. Aristizabal.
(2026) “Cancer histone H2A.Z missense mutations disrupt function through distinct local and allosteric
effects” Research Square. https://doi.org/10.21203/rs.3.rs-8484515/v1

Topics

  • Computational biology
  • Genomics
  • Molecular biology
  • Molecular genetics